您对肌肉和关节疼痛的CBD主题指南

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By now, you’ve当然听到了一些关于CBD的嗡嗡声，被称为奇迹工人的大麻衍生成分，作为抗炎剂，抗炎症治疗和之间的一切。您可以在口腔酊剂中找到它，在主流的砂砾商店中销售的粘性糖果，身体油和奶油 - 不再只是您当地的健康食品或维生素店。

“销售数据表明，CBD市场正在迅速增长，并且有很多互联网论坛，其中使用这些产品的人讨论他们为他们工作，”行为药理学研究单位的研究人员博士学位说在约翰霍普金斯湾景观医疗中心。所以，如果你处理慢性肌肉和关节疼痛，例如，类风湿关节炎or多发性硬化症那you may be wondering if slathering some directly on your achy areas can help you get some relief as an alternative to typical pain meds.

We asked top docs to weed out the speculation from the real science, so you can decide if CBD is for you.

首先，什么是CBD？

大麻矮小，爱游戏ayx官网 。Unlike its cousin, tetrahydrocannabinol (THC), another well-known cannabinoid found in the marijuana plant, CBD doesn’t get you high. It’s not a psychoactive. You can get CBD from both the hemp and marijuana plants (side note: these two shrubs are in the same plant family), but when derived from hemp, there’s only trace amounts of THC (the legal limit is .3%). Marijuanna typically may contain 15% THC. CBD from marijuana will obviously contain a bit more THC. CBD has been linked to many benefits including helping with insomnia,anxiety，抑郁症，癌症相关的副作用，和pain relief。

How Does CBD Work on Chronic Joint and Muscle Pain?

“我们有一个内源性大麻系统[a.k.a. endocannabinoid system]在我们的身体内,”布鲁斯说Solitar,医学博士,rheumatologist and clinical associate professor of medicine at NYU Grossman School of Medicine in New York City. “That means we have cannabinoid receptors throughout our organs and tissue,” he says.

They’re in your skin, as well as the lungs and brain. (This is the reason why marijuana gives you the munchies or makes you sleepy—the phtyocannabinoid THC interacts with those brain receptors.) “As a rheumatologist, I’ve been interested in this because there are cannabinoid receptors in the joints and nerves.”

We don’t know for sure, but CBD likely blocks some of the effect in those nerves, resulting in less pain, he says. CBD may work similarly to other medications we take for pain, or even topical analgesics, but the plant-based ingredient may be more appealing for someone who prefers to take a natural approach to pain management.

What Does Science Say About CBD and Chronic Pain?

专家很快指出，对慢性疼痛，特别是局部CBD的CBD研究非常有限。在期刊中审查Antioxidants已证实CBD具有减少炎症的机制
实验条件，但局部应用时可以帮助吗？研究很苗条。我们最接近的是：一只动物研究欧洲痛苦杂志表明，当CBD凝胶透皮涂抹于具有关节炎的大鼠皮肤时，它会切断膝关节疼痛，肿胀和炎症。

It’s important to note that a transdermal applicationisspecifically designed to deliver medicine into the bloodstream versus an ointment or cream which isintended to have local effects on the skin. Another small study on humans showed that CBD oil applied topically made a significant improvement in the pain, itch, and cold sensations in those with peripheral neuropathy (nerve damage that causes pain and numbness in their lower extremities). Not so promising: Aphase 2 trial of a prescription CBD gel用透皮斑块应用，与安慰剂相比，患有透皮贴片的人没有显着减少膝关节骨关节炎的人的疼痛。

因此，直到更大的规模，同行评审研究已经完成，医生对局部CBD持怀疑态度。“特别是商业产品，只有不够的临床证据备份任何关节和肌肉疼痛的索赔，”斯威尔博士说。“这并不是说他们没有效力，但没有临床研究证明他们是”。“

The other issue with topical CBD is its lack of regulation. The only FDA-approved CBD product is a pharmaceutical drug made for epilepsy patients. That means all the creams, oils, and balms you see on shelves aren’t FDA-approved.

目前，没有明确的CBD应该在产品中的明确指导方针，申请何时申请等等，“这些产品非常不准确地标记着大量的次数，”主轴博士说。“人们经常在他们身上花费很多钱，你甚至不知道产品中的CBD数量，”他说。一项研究贾玛showed that of 31 CBD-containing products, only 1/3 of them actually contained the amount of CBD listed on the label.

所以，如果你要试试，你应该寻找什么？

“制剂产品，应用量，应用现场和其他因素可能会影响吸收和效果，但没有任何真实数据，难以推测，”主轴博士说。与此同时，您可以使用一些有用的提示：

You want to see the word cannabidiol (or CBD) on the ingredient list and a standardized extraction ratio. You may see words like hemp, hemp seed oil, or hemp butter, but those terms don’t necessarily mean your product contains pure CBD. Ideally, you want to get your CBD products from a reputable source with a third-party lab certificate to verify that it actually contains what it says it does (the label will likely say it has a certificate of authenticity or COA, typically available on the site’s website, or include a QR code to view).

至于您的产品应包含多少CBD？专家还不知道。上面提到的大鼠研究包括一个非常繁体的剂量（对于一只小鼠，高达62毫克），可能比你在当地药店的奶油中找到更多。在具有遗传阶的儿童中进行的研究使用过透皮凝胶，剂量范围为50mg-250mg。

Are There Any Risks?

因为配方会很大，找到一种CBD主题，有助于您的疼痛关节和肌肉可能需要一些试验和错误。罗利士博士仍然说，“在事物的方案中，局部CBD可能是低风险，奖励潜力相当高。”但谨慎对抗过敏反应，特别是如果你有敏感的皮肤，并且你不想申请局部治疗以打开伤口，或者如果你有牛皮癣等皮肤状况，则会增加。

专家说，局部乳霜和软膏应该造成的风险低于口服CBD产品，但仍然是在使用前由您的医生运行。

遇见我们的作家

Krista Bennett Demaio.

Krista Bennett Demaio.has well over a decade of editorial experience. The former magazine-editor-turned-freelance writer regularly covers skincare, health, beauty, and lifestyle topics. Her work has appeared in national publications and websites includingOprah那Women’s Health那红色的书那形状那Dr. Oz The Good Life，bhg.com和prevention.com。她住在纽约亨廷顿，和她的丈夫和三个女儿。

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