我可以在甲氨蝶呤上使用哪些寒冷的补救措施？
题：
我是新的到ra。在过去，当我觉得我感冒了时，我已经使用了echinacea。我读到了我收到的信息小册子，因为我的处方对甲氨喋呤表示我不应该使用它。现在我感冒了，想知道我可以使用的符合反应的补救措施。我曾经也使用Alka-Seltzer Plus并想知道我是否可以使用它。我非常沮丧，因为我很长时间没有冷。我也在泼尼松，只希望仅限短期。
-Kathi
Answer:
Dear Kathi,
Dealing with a cold or the flu when you have rheumatoid arthritis (RA) can be a challenge. The condition itself makes you more susceptible to infection and catching contagious illnesses, as well as often making it harder to recover from one. Add an immunosuppressant, such as prednisone, methotrexate or biologics — which would make the immune system weaker — and things could get more complicated.
RA is an autoimmune disease. This means that the immune system attacks the body’s tissues as if they were foreign invaders or bacteria. In RA, this attack causes inflammation that can damage joints andother systems, such as internal organs。控制炎症的最佳方法是用药物，如疾病修饰的抗甲酸异常，生物学和生物仿制物等疾病。
Some of these medications — methotrexate, biologics, and to a lesser extent, steroids — are immunosuppressants. They have been designed to suppress the immune system’s activity and therefore its attack on the tissues in your body. When the immune system is suppressed, so is the RA, hopefully bringing you into缓解。缺点是这些药物工作的方式也使您更容易感染，例如感冒或流感。
Immune system boosters and RA
[Colds]are caused by the rhinovirus, which is especially present in the winter months. When this virus is present, your immune system will send out white blood cells to defend against it, but if you haven’t been exposed to this exact virus before, the result is a cold.
The idea behind immune system boosters, such as echinacea and golden seal, is that they will stimulate the cells that fight infection, such as white blood cells. Therefore, the immune system will be better able to fight back against the impending cold and prevent you getting sick.
Research into the effectiveness of echinacea is inconsistent. Some studies indicate that echinacea is no better than a placebo, but a large study showed that it may reduce both how many colds you have and how bad they are by as much as 25 percent. However, you need to be careful taking herbal supplements as they are less standardized and can be mixed with compounds that interact dangerously with your RA medications. Consult your physician before taking these supplements.
如果您有RA或其他自身免疫性疾病，您不使用ESHINACA很重要。无论研究如何进入海胆痤疮的疗效，广泛的一致认为，免疫系统助推器可能导致具有自身免疫疾病的人的耀斑。
In such conditions, the immune system attacks itself. If you increase the immune response to combat the cold, you can also expect the attack on your body to become more severe. Also, as methotrexate and biologics suppress the immune system and therefore suppress your RA, taking echinacea[could counteract the effects of the medication]。
Cold remedies and RA
There is generally not an interaction between over-the-counter cold medication and immunosuppressant medications, such as methotrexate. However, it’s important to be aware that cold medication usually contains acetaminophen — the generic name for Tylenol. If you are using acetaminophen as a painkiller, also using cold medication can put more of this medication into your body than it can handle. Too much acetaminophen can become an overdose and be toxic to your liver.
In additiona, some of the remedies contain nonsteroidal anti-inflammatory drugs (NSAIDs) such as Ibuprofen, Motrin, and Advil, which can cause kidney and liver damage and will result in toxicity due to Methotrexate.
Speak to your pharmacist or your doctor regarding what other cold remedies you can take. In the meantime, drink lots of fluids, make sure you get plenty of vitamin C and rest as much as you can.
You may also want to speak to your rheumatologist about whether they recommend skipping methotrexate while you are having a cold. Rheumatologists seem to differ on this — some want you to stop your medication only if you have a fever or are taking antibiotics, whereas others recommend skipping a dose if you are sick.
您应该知道：上面的答案提供了一般健康信息，不旨在取代合格的医疗保健专业人员的医疗建议或治疗建议。
您应该知道：上面的答案提供了一般健康信息，不旨在取代合格的医疗保健专业人员的医疗建议或治疗建议。
