Why Does MS Make My Legs Hurt?
疼痛是A.common symptom that affects people of all walks of life. It can be acute (sudden) or chronic (lasting more than three months). Pain can be a warning signal that you are injured, or it may result from miscommunication between the brain and body. Intensity of pain can range from mild to severe, and treatment of pain depends upon its origin.
常见的疼痛包括伤害性疼痛和神经源性疼痛:
Nociceptive pain is caused by activation of nerve receptors that transmit information about trauma or injury to the brain. Nociceptive pain can be somatic (involving the body surface or musculoskeletal system) or visceral (involving internal organs). Examples of somatic pain include joint and muscle pain, pain due to excessive activity or trauma, or pain due to inflammation, spasticity, or paralysis. Visceral pain originates from pain receptors within the chest, abdomen, or pelvic areas. It is often vague and might be described as pressure-like, deep squeezing, dull, or diffuse.
神经源性疼痛,也称为神经性疼痛或中枢疼痛,是由中环或外周神经系统的病变,损伤或疾病引起的。神经源性疼痛的例子包括paresthesia(例如,麻木,刺痛,燃烧,瘙痒),发敏神(例如,触摸的异常感觉或畸变),三叉神经痛(即疼痛影响脸部神经)和视神经炎。神经性疼痛可能来自中枢神经系统中的病变或由压缩神经产生(如腕管综合征)。脊髓病变导致的疼痛可能会感受到其他地方(例如,在皮肤表面,在躯干上或肢体上)。
Pain in multiple sclerosis
疼痛是A.common symptom that affects up to two-thirds of people with multiple sclerosis (MS), according to the多发性硬化国际联合会(MSIF)。MS的疼痛可以是阵发性(突然或经常发生的强化)症状)或可能变得慢性。当疼痛感到阴险时,它会影响生活质量和一个人的情绪。
Most common types of pain in MS include:
神经性疼痛,包括针和针,燃烧,瘙痒,刺,麻木,刺痛,疼痛,悸动,触感敏感度,感觉异常,痛苦(如在女士拥抱), or headache
肌肉骨骼疼痛,肌肉弱点或疲劳,痉挛,刚度,关节疼痛,背部疼痛或姿势差
阵发性疼痛,如三叉神经痛或滋补痉挛
l'hermittes标志被描述为当颈部弯曲胸部时,被描述为沿着脊柱行进并进入肢体
光学神经炎,是MS的常见症状,导致眼睛后面的疼痛感觉到眼球变得更糟
Why do my legs hurt?
People living with MS can experience different types of pain in the limbs (legs or arms), the most common of which are neuropathic or musculoskeletal in origin. Neuropathic pain in MS is frequently caused by脊髓的病变并且是感觉变化的特征。脊髓病变也可能导致肌肉无力,痉挛,共济失调或其他步态紊乱,每个障碍会导致肌肉骨骼问题。
你经历过燃烧,瘙痒,麻木,刺痛,刺伤,或腿部虫子的感觉吗?这些是感觉同性恋的例子,一种神经性疼痛的形式,并且经常被MS的人所经历。特别奇怪的感觉是腿部滴落的水的感觉,这是一种破坏性的含膜。其他透镜涉及感觉异常解释,对触摸的超敏反应,或紧密扎带。
患神经病理疼痛和感官变化通常用抗癫痫药物治疗,例如加巴亨坦,普瑞巴林,卡巴马嗪,钛烷或克隆泮和某些抗抑郁药。
对我来说,痉挛是腿部肌肉骨骼疼痛的重要来源。与MS相关的肌肉骨骼疼痛的其他原因包括姿势差,步行效率低(步态),物理不活跃,肌肉过度(异形),以及肌肉疲劳或弱点。
运动,物理治疗和放松技术可以帮助解决肌肉骨骼疼痛。虽然“正常”疼痛和疼痛可能会用湿热,冰和休息,镇痛药或抗炎药物治疗,但spasticity通常用甲基氯芬,二嗪泮,温和拉伸和运动进行治疗。
虽然MS肯定是腿部疼痛许多不同类型的疼痛的来源,但这不是痛苦的唯一可能的原因。腿部疼痛的其他原因包括血栓,静脉曲张,循环不良,物理损伤或感染,或背部疼痛。
一种罕见,但非常痛苦,可能与皮质类固醇治疗有关的病症是osteonecrosis,也称为血管坏死。在骨折坏死中,降低了骨骼或关节的血流,骨骼开始消失并分解。骨头字面上开始崩溃。不幸的是,骨囊坏死的症状可能归因于MS,可以延迟诊断。
如果您在腿部体验疼痛,请与您的医生讨论您的症状。
来源:
“MS Pain.” Multiple Sclerosis International Federation. Web. Accessed at Feb. 17, 2017https://www.msif.org/about-ms/symptoms-of-ms/pain/
Sahraian MA, Yadegari S, Azarpajouh R, Forughipour M. Avascular necrosis of the femoral head in multiple sclerosis: report of five patients.Neurol Sci.2012;33(6):1443-6。DOI:10.1007 / S10072-011-0914-8。Epub 2011 Dec 31.