你被忽视的主动脉

经过威廉戴维斯,M.D. 健康专业人士

胸主动脉是身体最大的动脉。它生活在胸部内,在胸前做的是将血液从心脏输送到身体的所有其他动脉。主动脉位于胸骨下方,最初在心脏上方,随着它的目标,然后向左和向下转向腹部,骨盆和腿部。

力量在体内可以削弱aort工作a. When the aorta is weakened, it enlarges. Enlarged aortas also tend to grow atherosclerotic plaque. Plaque in the aorta poses risk for stroke and mini-strokes ("transient ischemic attacks," or TIAs), since plaque is prone to fragmentation that releases little bits of debris that usually flow up into the arteries of the brain.

Enlarged aortas are fairly common, particularly in people with high blood pressure and cholesterol abnormalities, as well as those who are overweight or smoke. The simplest method to be screened for an enlarged aorta is with ultrasound of the heart, anechocardiogram。可以易于看出两个主动脉的第一英寸。

Conventional thinking is that, once an aorta enlarges (3.7 cm or greater is the cutoff), it will inevitably continue to enlarge at the average rate of 2.0 mm per year (adding up to 1.0 cm enlargement over 5 years). Once the aorta reaches 4.5 cm in diameter, it is classified as ananeurysm。因此,关于胸主动脉瘤的常规讨论所有讲述类似“每年都会监测扩大主动脉动脉瘤的话题。当主动脉达到5.5厘米的直径时,外科替换应进行。”

This is because an aortic diameter of 5.5 cm is associated with much greater likelihood of rupture. Ruptured aortic aneurysms are fatal within just a few minutes. Alternatively, the internal lining of the enlarged, weakened aorta can tear, a "dissection," in which the tissue-thin lining of the diseased aorta tears away, allowing blood to get beneath it and "dissect" along the length of the aorta. This is excruciating and can be life-threatening if not remedied immediately. Surgery for both aortic aneurysms and dissections involves opening the chest and usually replacing the aortic valve and inserting a synthetic aorta. The procedure is high-risk, especially if any branch arteries of the aorta are involved.

因此,停止任何进一步的主动脉扩大是一个有价值的目标。传统的思想是存在没有你可以做到阻止胸主动脉的不可避免的增长。“¨官。有很多努力,你可以停止进一步增加主动脉直径并最小化,如果不是排除,开发动脉瘤或解剖主动脉的风险。

There are two categories of factors that cause the aorta to become weakened and increase in diameter:

1)内部压力

将血压(BP)视为该主动脉“气球的内部充气压力。保持“充气压力”,即血压,低的对气动直径的增长施加大量影响。我的目标是使BP低(小于130/80,最好是100/70)。(虽然这可能看起来是极端的现代化的一天标准,但是生活自然猎人的生活方式的人类通常为90-110收缩,60-75舒张。)

2) Factors that weaken the aortic wall

炎症,脂蛋白沉积和营养缺乏等方法,以削弱主动脉的支持性组织。这些因素的校正有助于使主动脉壁保持弱化,减慢或停止任何放大和抑制动脉粥样硬化斑块的形成。这些步骤包括:

  • Correction of lipoprotein abnormalities(例如,小LDL和脂蛋白(a)) - 注意,这与校正“胆固醇”异常不同。胆固醇不会引起心脏病;脂蛋白(含脂质蛋白质)引起心脏病。胆固醇只是测量的便利性。测量和量化脂蛋白提供了真正的洞察主动脉如何削弱。您将不得不要求医生专门命令这种血液测试。

  • Reductions in carbohydrate intake- 减少血糖,从而减少糖化,或蛋白质的葡萄糖改性,导致炎症的情况。我赞成消除小麦,玉米淀粉和糖制成的所有产品,这也是纠正小型LDL,低HDL和高甘油三酯的极具有效的方法。

  • "Normalization" of vitamin D- 维生素D的恢复有助于抵消削弱它的主动脉壁中的炎症反应。我的目标是血液25-羟基维生素D水平为60-70ng / ml。达到该水平所需的维生素D的剂量因个体而异,但剂量通常为每天4000至8000单位。

  • 维生素C补充- Collagen crosslinking for aortic wall strength requires adequate vitamin C. A simple supplement (e.g. 500 mg) of a naturally-sourced vitamin C, along with plentiful vegetables and some fruit, should do it.

  • Omega-3 fatty acids from fish oil- 鱼油校正斑块的多种原因,特别是脂蛋白的脂蛋白衍生来自过量的甘油三酯。我使用每天1800毫克的最小OMEGA-3(EPA和DHA)或更多。

我患有初始扩大的主动脉率超过10年的患者。虽然它似乎有点复杂,但只有一些努力,如上所列的努力可能会使你的主动脉保持健康。

遇见我们的作家
威廉戴维斯,M.D.

William R. Davis is a Milwaukee-based American cardiologist and author. He wrote for HealthCentral as a health professional for Heart Health and High Cholesterol.